SERVImed - CF X-linker - crosslinking-laite

SERVImed - CF X-linker - crosslinking-laite

CF X-LINKER on yksi markkinoiden kattavimmista hoitolaitteista sarveiskalvon keratoconuksen ja ektasian hoitoon. Sen monipuoliset ja kustomoitavat toimenpidevaihtoehdot mahdollistavat räätälöitävät valokovetushoidot potilaan yksilöllisten tarpeiden mukaisesti. 

Ainoana maailmassa, CF X-LINKER:stä löytyy myös nopea, yksilöllisesti kustomoitu sekä matalatehoinen topo-/paky-ohjattu EPI-ON -toimenpide, Custom Fast CXL (cfCXL)*. Se on todistettu turvalliseksi ja toimivaksi lukuisissa eri kansainvälisissä tutkimuksissa, mukaan lukien seitsemän vuoden follow-up study. Custom Fast CXL -toimenpiteessä käytetään SERVImedin omia RIBOCROSS TE®/RIBOFAST® -riboflaviineja. Laitteen muissa toimenpiteissä voi vapaasti käyttää kaikkia markkinoilta löytyä riboflaviineja, ilman ylimääräisiä piilokustannuksia tai lisenssimaksuja.

Kirjallisuutta: 

• Carmine Ostacolo, Ciro Caruso, Diana Tronino, Salvatore Troisi, Sonia Laneri, Luigi Pacente, Antonio Del Prete, Antonia Sacchi “Increasing of corneal permeation of riboflavin-5′-phosphate through enhancers: A promising approach in corneal trans-epithelial cross-linking treatment” Inter J Pharm 440 (2013) 148– 153.
• Ciro Caruso, Carmine Ostacolo, Robert L. Epstein, Gaetano Barbaro, Salvatore Troisi, Decio Capobianco: “Transepithelial Corneal Cross-Linking With Vitamin E-Enhanced Riboflavin Solution and Abbreviated, Low-Dose UV-A: 24-Month Clinical Outcomes” Cornea 2016;35:145–150.
• Ciro Caruso, Gaetano Barbaro, Robert L. Epstein, Diana Tronino, Carmine Ostacolo, Antonia Sacchi, Luigi Pacente, Antonio Del Prete, Marina Sala, Salvatore Troisi: “Corneal Cross-Linking: Evaluating the Potential for a Lower Power, Shorter Duration Treatment” Cornea 2016;35:659–662.
• Ciro Caruso, Robert L. Epstein, Carmine Ostacolo, Luigi Pacente, Salvatore Troisi, Gaetano Barbaro. “Customized Corneal Cross-linking – A Mathematical Model” Cornea 2017; 36:600–604.
• Roy S. Rubinfeld, Ciro Caruso, Carmine Ostacolo “Corneal Cross-Linking – The Science Beyond the Myths and Misconceptions” Cornea 2019 Jun;38(6):780-790.
• Ciro Caruso, Robert L. Epstein, Pasquale Troiano, Carmine Ostacolo, Gaetano Barbaro, Luigi Pacente, Silvia Bartollino, Ciro Costagliola “Topography and Pachymetry Guided, Rapid Epi-on Corneal Cross-Linking for Keratoconus: 7-year Study Results” Cornea 2020;39:56–62.
• Ciro Caruso, Ciro Costagliola, Salvatore Troisi, Robert L. Epstein “Compaction of very thin corneas from ultraviolet A riboflavin-vitamin E transepithelial cross-linking” Experimental Eye Research 205 (2021) 108484.
• Ciro Caruso, Robert L. Epstein, Pasquale Troiano, Francesco Napolitano, Fabio Scarinci, Ciro Costagliola “Topo-pachimetric accelerated EPI-ON cross-linking compared to the Dresden protocol using riboflavin with Vitamin E TPGS: results of a 2-year randomized study” J. Clin. Med. 2021, 10, 3799.

Esitelmät:

• Ciro Caruso, Salvatore Troisi, Antonio Del Prete, Luigi Pacente, Gaetano Barbaro, Carmine Ostacolo, Salvatore Del Prete “Evaluation of the penetration through human cornea of riboflavin 0.1% in solution with other molecules after trans-epithelial application”. 1st EuCornea Congress, June 17-19 2010, Venice, Italy
• Robert L. Epstein, Salvatore Del Prete, Ciro Caruso, Salvatore Troisi, Carmine Ostacolo, Luigi Pacente, Antonio Del Prete, Gaetano Barbaro “Thickness and ultra-structural changes in keratoconus-affected human corneas after transepithelial cross-linking” American Academy of Ophthalmology Annual Meeting, October 2010, Chicago (P0073).
• Robert L. Epstein, Ciro Caruso, Carmine Ostacolo, Salvatore Troisi, Luigi Pacente, Gaetano Barbaro, Antonio Del Prete, Antonia Sacchi: “A new riboflavin solution for trans-epithelial cross-linking: a study of corneal pharmacokinetic” American Academy of Ophthalmology Annual Meeting, October 2010, Chicago (P0073).
• Salvatore Del Prete, Ciro Caruso, Luigi Pacente, Salvatore Troisi, Antonio Del Prete, Gaetano Barbaro “Effects of UV-A rays on the corneal epithelial surface after topical application of riboflavin solutions: an electron microscope study”. American Academy of Ophthalmology Annual Meeting, October 2010, Chicago (P0073)
• Gaetano Barbaro, Ciro Caruso, Salvatore Troisi, Antonio Del Prete, Luigi Pacente “A Mathematical Model of Corneal UV-A Absorption After Soaking With a Riboflavin Solution During Trans-epithelial Cross-linking”. 1st Refractive Online and SICSSO Joint International Congress, July 7-9, 2011, Grosseto, Italy (Best paper, podium presentation)
• Ciro Caruso, Salvatore Troisi, Gaetano Barbaro, Carmine Ostacolo, Antonio Del Prete, Luigi Pacente “UV-A rays absorption in human corneas before and after trans-epithelial riboflavin application: an experimental study”. 2nd Refractive Online and SICSSO Joint International Congress, June 28-30, 2012, Rome, Italy (Podium presentation)
• Ciro Caruso, Salvatore Troisi, Antonio Del Prete, Luigi Pacente, Gaetano Barbaro “Trans-epithelial cross-linking with riboflavin solution: one-year clinical results”. 1st Refractive Online and SICSSO Joint International Congress, July 7-9, 2011, Grosseto, Italy (Podium presentation)
• Ciro Caruso, Luigi Pacente, Robert L. Epstein, Salvatore Troisi, Gaetano Barbaro, Antonio Del Prete: “Trans-epithelial cross-linking with riboflavin solution: two-year clinical results” 2nd joint International Congress Refractive Online & SICSSO, Rome 2012 (podium presentation).

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